Reading the manual is the first step then ask questions. I use 40 gr of 3f as a target load out to 50 yards and up to 70 for 100Yds in th 50 cal. You may find your most accurate load by stepping up 5 gr at a time but generally theres no use sense in blasting 80 gr at a 25 yd six-bull. 3f burns a little cleaner. Even more important is your ball patch combo. Buddies find that the time honored .490 ball and .011 patch in a TC is quite accurate....sometimes a .495. This is something you'll have to work out for your rifle! My own custom rifle with deep rifling uses a .498 ball, 018 patch and 50 gr of 3f for max accuracy. This is too hard to load in the hunting field for follow up so the second load is a .490 ball, 012 patch and 85 gr of KiK or Goex 2f. This goes down easy over fouling and is plenty accurate.
I use a spit patch for target and wipe every 5 shots. If you try to drive a lubed patch ball down a fouled bore you're asking for trouble however a spit patch works like magic. You'll need a short starter and a stainless steel or brass range rod. Its hard to beat the new bore lube but prefer and mix of mutton and deer tallow.