The S&W 422 and 622 have fixed barrels and only need a thread adapter that replaces the barrel bushing/nut. Accurate guns. They were discontinued in 1996, I think, but still can be found at decent prices.
I have this one and a Ruger Silent SR, can't go wrong with that combination.
I've used a lot of VV N320 and N330, mostly in 9mm and .45ACP, cleanest burning powders I've ever used, little more expensive than the others, but not enough to keep me from using it.
When I run out of other powders, they will be replaced by VV.
The problem with measuring forces on the Italian guns and trying to tune to a certain value is the variability in the the tolerances of individual guns.
You have to tune the springs differently in each gun, find the balance between lever force and and setting off whichever primers you happen to be using.
The Uberti guns seem to have more in the way of guidelines than tolerances, also depends on whether that particular rifle was assembled before or after the three Chianti lunch.
And yes, after a lot of experience you get a pretty good feel for what will work and what won't.
That's Pike Coyle, and his wife Quicksand at the loading table. Owners of Thunderstick Trading Company down here in Tuscon.
Those were great matches up there in Williams.