Paco Kelly has some +P loads that will make your eyes water. Used the H110 load in my Rugers but had to back off a little to hold it in the Rossi. I know this is not exactly what you requested, but he goes into why the 45 kills the way it does on game animals. Taylor Knock Down out of Africa concept is good info and why the 45 will out perform 44 Mag with proper handloads. Loads he is working with should only be used in the full sized RV or the Redhawk.
Good read anyway you look at it... http://www.leverguns.com/articles/paco/45coltlevergun.htm